Symptoms Of Cervical Cancer And Uterine Cancer
Published on Apr 13 2010, in the categories: Methods of detection
Today the disease that causes the highest number of human deaths is certainly the cancer. The cancer is the disease of the 21 century. Until now, the doctors haven’t found a cure, because of the rapid multiplication capacity of the tumor cells. In a relatively short period of time the cancer affects all the cells of the organism and if is not diagnosed in the early stages it causes death. The cancer treatment is painful, the chemotherapy has very hard effects on the body, the patients will suffer hair loss, weight loss, teeth loss.
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The symptoms of the cervical cancer are:
-the loss of the appetite and the weight loss;
-unjustified tiredness;
-pelvic pain, back pain;
-bleeding, vaginal discharge;
-fractures may occur;
-the pain and the vaginal discharge occurring during the sexual intercourse (the Human Papilloma Virus infection may be present for a long period of time without any symptoms present, that’s why in the majority of cases the cancer is detected to late).
There are 2 main types of cervical cancer, but many other cancers may originate in the cervical area. The principal types of cervical cancers are: the cervical cancer with squamous cells and adenocarcinoma.
The infections with the Human Papilloma Virus are very dangerous because over 70% of the cancer cases are generated by the 16 and 18 types of the Human Papilloma Virus. The Human Papilloma Virus exists in over 250 types, but only the 16 and 18 type are responsible for generating cancer.
There are 2 types of treatment according to the evolution phase of the disease. In the incipient phase the treatment is to surgical remove the tumor; in advanced stages the treatment is radiotherapy and chemotherapy. There is another possibility of a combined treatment with Cisplatina and Hycamtin, for the cases when the disease has advanced to the 4th B stage. The survival ratio after 5 years from the cancer diagnosis is good, approximately 80-90% for the cancer cases discovered in the first stage and 50-65% for the cancer cases discovered in stage two. The forecast decrease in cancer cases discovered too late when the cancer formations have developed in metastasis.
All the doctors, no matter what their specialization, recommend us a healthy lifestyle, because a healthy lifestyle means a strong organism that may be able to fight with any disease. There were cancer cases when the disease disappeared without any treatment, because the organism fought through its self defense power with the disease.
The doctors recommend us a few simple, practical life rules:
-to adopt a poor meat diet and a rich fruits and vegetable diet;
-to drink at least 2 l of water per day (the water is very important because helps up to detoxify the organism)
-to take periodic medical controls for detect the disease in incipient phases
-to start the sexual life at an appropriate age and without having many different partners.
In Romania, there are 5 women who dye everyday because of the cervical cancer, and in Europe 40 women dye everyday because of these disease.
Like in many other disease cases it is advisable to prevent then to treat (we all have to take into consideration the fact that until now doesn't exist any treatment for the advanced stages).
The cancer is a very ruthless disease that doesn’t have a cure, and who can affect everybody no matter the age or sex.
<-336x280 Large Rectangle - center->
The symptoms of the cervical cancer are:
-the loss of the appetite and the weight loss;
-unjustified tiredness;
-pelvic pain, back pain;
-bleeding, vaginal discharge;
-fractures may occur;
-the pain and the vaginal discharge occurring during the sexual intercourse (the Human Papilloma Virus infection may be present for a long period of time without any symptoms present, that’s why in the majority of cases the cancer is detected to late).
There are 2 main types of cervical cancer, but many other cancers may originate in the cervical area. The principal types of cervical cancers are: the cervical cancer with squamous cells and adenocarcinoma.
The infections with the Human Papilloma Virus are very dangerous because over 70% of the cancer cases are generated by the 16 and 18 types of the Human Papilloma Virus. The Human Papilloma Virus exists in over 250 types, but only the 16 and 18 type are responsible for generating cancer.
There are 2 types of treatment according to the evolution phase of the disease. In the incipient phase the treatment is to surgical remove the tumor; in advanced stages the treatment is radiotherapy and chemotherapy. There is another possibility of a combined treatment with Cisplatina and Hycamtin, for the cases when the disease has advanced to the 4th B stage. The survival ratio after 5 years from the cancer diagnosis is good, approximately 80-90% for the cancer cases discovered in the first stage and 50-65% for the cancer cases discovered in stage two. The forecast decrease in cancer cases discovered too late when the cancer formations have developed in metastasis.
All the doctors, no matter what their specialization, recommend us a healthy lifestyle, because a healthy lifestyle means a strong organism that may be able to fight with any disease. There were cancer cases when the disease disappeared without any treatment, because the organism fought through its self defense power with the disease.
The doctors recommend us a few simple, practical life rules:
-to adopt a poor meat diet and a rich fruits and vegetable diet;
-to drink at least 2 l of water per day (the water is very important because helps up to detoxify the organism)
-to take periodic medical controls for detect the disease in incipient phases
-to start the sexual life at an appropriate age and without having many different partners.
In Romania, there are 5 women who dye everyday because of the cervical cancer, and in Europe 40 women dye everyday because of these disease.
Like in many other disease cases it is advisable to prevent then to treat (we all have to take into consideration the fact that until now doesn't exist any treatment for the advanced stages).
The cancer is a very ruthless disease that doesn’t have a cure, and who can affect everybody no matter the age or sex.
Cervical Cancer Screening
Published on Mar 16 2010, in the categories: Facts, Methods of detection, Useful info, diagnosis
Screening for cervical cancer of the uterus - Cervical cancer is `the second most common cancer worldwide among women in terms of frequency, behind breast cancer and tied with Colorectal Cancer. Nearly 400 000 new cases are diagnosed each year, including a large proportion of the poor, whether in countries in developing or industrialized.
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The standard method of detecting breast cancer, used for fifty years, is to visually examine hundreds of thousands of cells for each patient (morphological examination) in search of small variations in shape and size of cells and nuclei that signal precancerous cells and cancer. This method is called a Pap smear, named after its inventor Dr. G. Pap `s that has developed in the 1940s. In common parlance, we speak more readily of "smear" in reference to the method of sampling cells.
Early diagnosis of cervical cancer of the uterus is `indispensable to a good prognosis. The early detection programs are therefore designed to identify women at risk and those with the earliest stages of the disease. Each year, we realize at least 140 million Pap tests in the world. The establishment of programs for prevention and early detection of morphological abnormalities of cervical cells has reduced d `70` l% incidence of cervical cancer.
Despite this considerable success, current methods of screening and diagnosis of cervical cancer have recognized limitations, resulting in an unacceptable rate of false negatives and false positives and high cost. Indeed, the current tests involve a high degree of subjectivity and does not detect direct markers of the disease.
Research papillomavirus (HPV) has recently been adopted to elucidate the results of cytology unclear or slightly abnormal (most of which are false positives) among women over 35 years. It has been demonstrated that high-risk HPV (HR-HPV) were the main etiological factor for cervical cancer `s uterus.The search of `HPV in this application is limited to a small percentage of smears. The sensitivity of the search for the `HPV disease is greater than the Pap test. That said, the high prevalence of infection with HPV `l in women (up to 25%) leads to a very low specificity (correlation between a positive test and the actual disease), which severely limits the potential clinical usefulness This early detection.
We know that `the persistence of infection with HPV high risk for several years is a causal factor of cervical cancer` s womb. The objectivity of early detection of the disease should be significantly improved compared to current approaches, based on a subjective interpretation of morphologic cervical cells or on a risk assessment based on the presence of HPV. To detect and diagnose cancer earlier cervical `s womb, it is more efficient to detect specific biomarkers that indicate the presence or absence of` this type of cancer or its precursors.
Mtm laboratories has identified p16INK4a as a marker potential direct and developed a family of technologies for screening and diagnosis based on this biomarker. The techniques of diagnosis and early detection based on this marker promise a safe and accurate diagnosis of the disease. The diagnostic kits of mtm laboratories use the clone d `E6H4TM antibodies, highly selective and sensitive to the presence of p16INK4a, whose value has been demonstrated clinically. Unlike other possible antibodies, detection with E6H4TM shows no cross reactivity with Trichomonas (Protozoa causing vaginal infections), which causes an excessive number of false positives and rendered the antibody in question.
<-336x280 Large Rectangle - center->
The standard method of detecting breast cancer, used for fifty years, is to visually examine hundreds of thousands of cells for each patient (morphological examination) in search of small variations in shape and size of cells and nuclei that signal precancerous cells and cancer. This method is called a Pap smear, named after its inventor Dr. G. Pap `s that has developed in the 1940s. In common parlance, we speak more readily of "smear" in reference to the method of sampling cells.
Early diagnosis of cervical cancer of the uterus is `indispensable to a good prognosis. The early detection programs are therefore designed to identify women at risk and those with the earliest stages of the disease. Each year, we realize at least 140 million Pap tests in the world. The establishment of programs for prevention and early detection of morphological abnormalities of cervical cells has reduced d `70` l% incidence of cervical cancer.
Despite this considerable success, current methods of screening and diagnosis of cervical cancer have recognized limitations, resulting in an unacceptable rate of false negatives and false positives and high cost. Indeed, the current tests involve a high degree of subjectivity and does not detect direct markers of the disease.
Research papillomavirus (HPV) has recently been adopted to elucidate the results of cytology unclear or slightly abnormal (most of which are false positives) among women over 35 years. It has been demonstrated that high-risk HPV (HR-HPV) were the main etiological factor for cervical cancer `s uterus.The search of `HPV in this application is limited to a small percentage of smears. The sensitivity of the search for the `HPV disease is greater than the Pap test. That said, the high prevalence of infection with HPV `l in women (up to 25%) leads to a very low specificity (correlation between a positive test and the actual disease), which severely limits the potential clinical usefulness This early detection.
We know that `the persistence of infection with HPV high risk for several years is a causal factor of cervical cancer` s womb. The objectivity of early detection of the disease should be significantly improved compared to current approaches, based on a subjective interpretation of morphologic cervical cells or on a risk assessment based on the presence of HPV. To detect and diagnose cancer earlier cervical `s womb, it is more efficient to detect specific biomarkers that indicate the presence or absence of` this type of cancer or its precursors.
Mtm laboratories has identified p16INK4a as a marker potential direct and developed a family of technologies for screening and diagnosis based on this biomarker. The techniques of diagnosis and early detection based on this marker promise a safe and accurate diagnosis of the disease. The diagnostic kits of mtm laboratories use the clone d `E6H4TM antibodies, highly selective and sensitive to the presence of p16INK4a, whose value has been demonstrated clinically. Unlike other possible antibodies, detection with E6H4TM shows no cross reactivity with Trichomonas (Protozoa causing vaginal infections), which causes an excessive number of false positives and rendered the antibody in question.